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Resource Library / Validating Digital Droplet PCR (ddPCR) Assay with Zero-Inflated Poisson Model

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Validating Digital Droplet PCR (ddPCR) Assay with Zero-Inflated Poisson Model

The purpose of this study was to develop a better model to improve the quality of ddPCR assay validation, involving how to improve the reliability of accuracy, precision, and sensitivity.

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Validating The Simoa Technology
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Validating The Simoa Technology
The Simoa system is ultra-sensitive, and capable of detecting and quantifying challenging ...
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A GxP-Qualified dPCR-Based RCL Assay to Quantify Replication Competent Lentivirus in Bioanalytical Samples
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A GxP-Qualified dPCR-Based RCL Assay to Quantify Replication...
Lentiviral vectors are widely used in gene and cell therapy for diseases like HIV, cancer,...
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Empowering immune monitoring with ELISpot assays
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Empowering immune monitoring with ELISpot assays
The emergence of global pandemics has led to an expansion of studies focused on vaccine de...
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Measuring Biological Activity of Biopharmaceuticals with Cell-Based Assays
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Measuring Biological Activity of Biopharmaceuticals with Cell-Based...
A drug’s potency, which is a critical quality attribute, is determined by examining biol...
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Qualification of the Quanterix Phospho-Tau 217 (pTau-217) assay using the Simoa HD-X platform
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Qualification of the Quanterix Phospho-Tau 217 (pTau-217) assay using...
Alzheimer’s disease (AD) is a neurodegenerative disorder which stands as one of the most...
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Quantitative Assessment of mRNA Drug Biological Activity by Cell-Based Assays​
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Quantitative Assessment of mRNA Drug Biological Activity by...
Biological activity of mRNA drugs, historically assessed via animal study, is critical to ...
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A Competitive Ligand-binding Assay for the Detection of Neutralizing Antibodies Against XTMAB-16
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A Competitive Ligand-binding Assay for the Detection of Neutralizing...
Frontage develops a full validation of the XTMAB-16 NAb (neutralizing antibody) assay with...
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pTau217 Biomarker Assay
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pTau217 Biomarker Assay
Frontage introduces a new ultrasensitive assay for the quantitative determination of pTau2...
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Biomarkers Assay List – May 2023
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Biomarkers Assay List – May 2023
Frontage offers an impressive list of biomarker assays. Download our ever-growing list of ...
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Immunoassays for Drug Discovery
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Immunoassays for Drug Discovery
Frontage supports early drug discovery with various immunoassays for proteins and therapeu...
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Testing of Carryover & After MRD Benchtop Stability for Pharmacokinetic Method Validation in Gyrolab Immunoassay Platform
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Testing of Carryover & After MRD Benchtop Stability for...
In this white paper, we show testing of two critical parameters for the method validation ...
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Utilizing Ligand Binding Assays (LBA) and Critical Reagents for Drug Development
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Utilizing Ligand Binding Assays (LBA) and Critical Reagents for Drug...
Critical reagents – the key components used in LBA – are central to ensuring the consi...
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