Discovery
Medicinal Chemistry Services
Discovery ADME
- Metabolic Stability
- CYP Interaction
- Permeability & Transporters
- Physicochemical Properties
- Protein Binding
Assay Results
Androstenone -
(Matrix: Porcine Fat tissue)
Analytes:
Androstenone
Matrix:
Porcine Fat tissue
Assay Range:
20- 5000 ng/g
Sample Volume:
500 mg
Anticoagulant:
NA
StorageTemp (oC):
-20/-70
Platform:
LC-MS/MS
Ang-1
IL-18
IL-1Ra
IL-2RA
IP-10
MCP-1
MIG
MIP-1β
NFL
VEGF-A -
(Matrix: Human Serum)
Analytes:
Ang-1
IL-18
IL-1Ra
IL-2RA
IP-10
MCP-1
MIG
MIP-1β
NFL
VEGF-A
Matrix:
Human Serum
Assay Range:
Ang-1: The LLOQ is 80.0 pg/mL (320 pg/mL in human serum) and the ULOQ is
272000 pg/mL (1088000 pg/mL in human serum);
IL-18: The LLOQ is 3.3 pg/mL (13.2 pg/mL in human serum) and the ULOQ is
4250 pg/mL (17000 pg/mL in human serum);
IL-1Ra: The LLOQ is 15.6 pg/mL (62.4 pg/mL in human serum) and the ULOQ is
3400 pg/mL (13600 pg/mL in human serum);
IL-2RA: The LLOQ is 10.0 pg/mL (40.0 pg/mL in human serum) and the ULOQ is
34000 pg/mL (136000 pg/mL in human serum);
IP-10: The LLOQ is 0.8 pg/mL (32.0 pg/mL in human serum) and the ULOQ is
2550pg/mL (10200 pg/mL in human serum);
MCP-1: The LLOQ is 1.9 pg/mL (7.6 pg/mL in human serum) and the ULOQ is
2550 pg/mL (10200 pg/mL in human serum);
MIG: The LLOQ is 8.3 pg/mL (33.2 pg/mL in human serum) and the ULOQ is
17000 pg/mL (68000 pg/mL in human serum); MIP-1β: The LLOQ is 15.6 pg/mL (62.4 pg/mL in human serum) and the ULOQ is
850 pg/mL (3400 pg/mL in human serum); NFL: The LLOQ is 63.0 pg/mL (252 pg/mL in human serum) and the ULOQ is
46578 pg/mL (186312 pg/mL in human serum);
VEGF-A: The LLOQ is 2.0 pg/mL (8.0 pg/mL in human serum) and the ULOQ is
1700 pg/mL (6800 pg/mL in human serum).
Sample Volume:
30 μL
Anticoagulant:
NA
StorageTemp (oC):
-70
Platform:
MSD
Angiotensin -
(Matrix: Rat Blood)
Analytes:
Angiotensin
Matrix:
Rat Blood
Assay Range:
2 ng/mL - 500 ng/mL
Sample Volume:
100 µL
Anticoagulant:
EDTA
StorageTemp (oC):
-20/-70
Platform:
LC-MS/MS
Ansofaxine/O-Desmethylvenlafaxine -
(Matrix: Human Plasma
Human Urine)
Analytes:
Ansofaxine/O-Desmethylvenlafaxine
Matrix:
Human Plasma
Human Urine
Assay Range:
0.1/0.5-100/500 ng/mL
1/5-1000/5000 ng/mL
Sample Volume:
100 µL
50 µL
Anticoagulant:
Sodium Heparin or K2EDTA with Citric Acid
Urine containing Citric Acid
StorageTemp (oC):
-80
Platform:
LC-MS/MS
Apatinib -
(Matrix: Human Plasma)
Analytes:
Apatinib
Matrix:
Human Plasma
Assay Range:
2-1000 ng/mL
Sample Volume:
50 µL
Anticoagulant:
Lithium Heparin
StorageTemp (oC):
-80
Platform:
LC-MS/MS
Apixaban -
(Matrix: Human Plasma)
Analytes:
Apixaban
Matrix:
Human Plasma
Assay Range:
0.2-200 ng/mL
Sample Volume:
50 µL
Anticoagulant:
K2EDTA
StorageTemp (oC):
-70
Platform:
LC-MS/MS
Apixaban -
(Matrix: Human Plasma)
Analytes:
Apixaban
Matrix:
Human Plasma
Assay Range:
0.4-160 ng/mL
Sample Volume:
50 µL
Anticoagulant:
K2EDTA
StorageTemp (oC):
-70
Platform:
LC-MS/MS
Apremilast -
(Matrix: Human Plasma)
Analytes:
Apremilast
Matrix:
Human Plasma
Assay Range:
1-600 ng/mL
Sample Volume:
50 µL
Anticoagulant:
Sodium Heparin
StorageTemp (oC):
-20/-70/-80
Platform:
LC-MS/MS
Apricoxib -
(Matrix: Human Plasma)
Analytes:
Apricoxib
Matrix:
Human Plasma
Assay Range:
2-1000 ng/mL
Sample Volume:
100 µL
Anticoagulant:
EDTA
StorageTemp (oC):
-20/-70
Platform:
LC-MS/MS
April -
(Matrix: Human Serum)
Analytes:
April
Matrix:
Human Serum
Assay Range:
60.00 to 1400 pg/mL
Sample Volume:
120 μL
Anticoagulant:
NA
StorageTemp (oC):
-70
Platform:
ELISA
Arginine/Citrulline -
(Matrix: Human Plasma)
Analytes:
Arginine/Citrulline
Matrix:
Human Plasma
Assay Range:
A/C-(150+125000)/(250+250000)
Sample Volume:
10 µL
Anticoagulant:
Heparin
StorageTemp (oC):
RT
Platform:
LC-MS/MS
Arginine/Citrulline -
(Matrix: Mouse Plasma)
Analytes:
Arginine/Citrulline
Matrix:
Mouse Plasma
Assay Range:
A/C-(A+125000)/(C+250000)
Sample Volume:
25 µL
Anticoagulant:
Heparin
StorageTemp (oC):
-20
Platform:
LC-MS/MS
Aripiprazole -
(Matrix: Human Plasma)
Analytes:
Aripiprazole
Matrix:
Human Plasma
Assay Range:
0.5-100 ng/mL
Sample Volume:
50 µL
Anticoagulant:
K2EDTA
StorageTemp (oC):
-70
Platform:
LC-MS/MS
Aripiprazole -
(Matrix: Human Plasma)
Analytes:
Aripiprazole
Matrix:
Human Plasma
Assay Range:
0.5-500 ng/mL
Sample Volume:
50 µL
Anticoagulant:
K2EDTA
StorageTemp (oC):
-20/-70
Platform:
LC-MS/MS
Arsenic -
(Matrix: Human Plasma)
Analytes:
Arsenic
Matrix:
Human Plasma
Assay Range:
5-500 ng/mL
Sample Volume:
80 µL
Anticoagulant:
K2EDTA
StorageTemp (oC):
-20/-70
Platform:
ICP-MS
Arsenic Trioxide -
(Matrix: Dog Plasma)
Analytes:
Arsenic Trioxide
Matrix:
Dog Plasma
Assay Range:
50-1000 ng/mL
Sample Volume:
30 µL
Anticoagulant:
K2EDTA
StorageTemp (oC):
-20/-70
Platform:
ICP-MS
As (III), DMA, MMA, As (V) -
(Matrix: Human Plasma)
Analytes:
As (III), DMA, MMA, As (V)
Matrix:
Human Plasma
Assay Range:
0.5-100 ng/mL
Sample Volume:
70 µL
Anticoagulant:
K2EDTA
Lithium Heparin
StorageTemp (oC):
-20/-70
Platform:
ICP-MS
As (Total ) -
(Matrix: Dog Plasma)
Analytes:
As (Total )
Matrix:
Dog Plasma
Assay Range:
50-10000 ng/mL
Sample Volume:
60 µL
Anticoagulant:
Sodium Heparin
StorageTemp (oC):
-20
Platform:
ICP-MS
As (Total ) -
(Matrix: Rat/Rabbit Plasma)
Analytes:
As (Total )
Matrix:
Rat/Rabbit Plasma
Assay Range:
50-10000 ng/mL
Sample Volume:
60 µL
Anticoagulant:
Sodium Heparin
StorageTemp (oC):
-20
Platform:
ICP-MS
Asenapine -
(Matrix: Human Plasma)
Analytes:
Asenapine
Matrix:
Human Plasma
Assay Range:
0.025-20 ng/mL
Sample Volume:
250 µL
Anticoagulant:
K2EDTA
StorageTemp (oC):
-20
Platform:
LC-MS/MS
Asimadoline / Asimadoline Glucuronide -
(Matrix: Human Plasma)
Analytes:
Asimadoline / Asimadoline Glucuronide
Matrix:
Human Plasma
Assay Range:
2/20-200/2000 ng/mL
Sample Volume:
50 µL
Anticoagulant:
EDTA
StorageTemp (oC):
-20/-70
Platform:
LC-MS/MS
Aspirin/Salicylic Acid -
(Matrix: Human Plasma)
Analytes:
Aspirin/Salicylic Acid
Matrix:
Human Plasma
Assay Range:
1/50-400/20000 ng/mL
1/50-1000/10000 ng/mL
Sample Volume:
100 µL
Anticoagulant:
NaF-EDTA
Heptafluorobutyric Acid
StorageTemp (oC):
-70
Platform:
LC-MS/MS
