IN Vitro Assessment of the inhibition of Human Organic Anion Transporting Polypeptide 1B1/1B3 by Highly Bound Plasma Proteins Compounds in the Presence of Physiological Concentration of Human Serum Albumin

The present study was aimed to validate this alternate approach to assess inhibition of organic anion transporting polypeptide 1B1/1B3 (OATP1B1/OATP1B3) by highly plasma protein-bound compounds is to run in vitro IC50 studies in a more physiologically relevant condition: the presence of 4% w/v human serum albumin (HSA)

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