Services & Solutions
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Drug Development
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Drug Metabolism & Pharmacokinetics (DMPK)
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In Vitro Services
In vitro based assays are designed to rapidly assess metabolic and transport pathways, permeability and drug-drug interaction potential.
At Frontage our scientists work closely with our sponsors in the development of early in vitro assays to assist lead optimization and candidate selection and to help assess development ‘risk’. These studies form an integral part of IND enabling studies
Discover the following In Vitro Services at Frontage
Metabolite Profiling and Identification
A key in supporting the development of your drug candidate.
Kinetics & Metabolic Stability
Evaluating pharmacokinetic parameters is essential for determining drug dosing and frequency.
Drug-Drug Interaction
Drug-drug interaction and evaluation is an important undertaking in drug development.
Permability and Transporters
Comprehensive transporter services to support projects from discovery to development.
Protein Binding and Blood Cell Partitioning
A determinant of both drug elimination and drug pharmacological activity.
Resources To Consider
fact-sheet
DMPK Services Fact Sheet
At Frontage, we offer extensive drug metabolism and pharmacokinetic capabilities for new c…
fact-sheet
Drug Transporters Services
Drug transporters can be major determinants of pharmacokinetics, drug-drug interactions, a…
application-notes
MIST Application Note
Regulatory agencies have made recommendations on when and how to identify and characterize…
