Technology Platforms
Cell Based Assays
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IN THIS SECTION
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We offer routine cell phenotyping, cell adhesion and migration, cell-potency, cell-based immunogenicity, organoid modeling, as well as single-cell genomics and cellular phenomics, such as scRNA-seq.
Phenotypic Cell Assays (R&D,Regulated, GxP)
- Apoptosis assays
- Necrosis assays
- Pyroptosis assays
- Ferroptosis assays
- Proliferation Assays
- Viability Assays
- Cell adhesion
- Cell migration
- Permeability assay
- Reporter assay
Stable cell line development (R&D)
- Development stable cell lines from biopsy samples.
- Viral transduction based cell line development.
- Chemo-resistance based cell line development.
- Virus-based induced pluripotent cell.
- Organoid modeling from biopsy samples and stem cells
Cell potency assay (regulated, GxP)
- Virus
- ADC drugs
- Biosimilar, e.g., insulin biosimilar drugs, cytokine similar drugs
- mRNA drugs, e.g., mRNA vaccines
Cell-based Neutralizing Antibody (NAb) Assays (regulated, GxP)
We offer a panel of cell based NAb assays, such as for biosimilar drugs, ADC drugs, oncolytic virus drugs, as well as custom-specific drug cellular function- based assays. We have extensive experience on NAb assays as follows.
- Cell proliferation based-NAb assays.
- Cell death based-NAb assays.
- Cell signal transduction based-NAb assays.
- Reporter-based NAb assays.
- Cell-western-based NAb assays.
- Virus-titer based-NAb assays.
Explore other Technology Platform Services from Frontage
![Flow Cytometry](https://www.frontagelab.com/wp-content/uploads/2024/05/Untitled-design-39.png)
Flow Cytometry
Supporting comprehensive quality assay development
![Ligand Binding Assay](https://www.frontagelab.com/wp-content/uploads/2024/05/Untitled-design-40.png)
Ligand Binding Assay
In the context of PK analysis, ligand binding assays are utilized to measure the concentration of a drug …
![Automation](https://www.frontagelab.com/wp-content/uploads/2024/05/Untitled-design-38.png)
Automation
Automation plays a crucial role in industries; it allows experiments to be completed faster and with fewer errors.
![Cell Based Assays](https://www.frontagelab.com/wp-content/uploads/2024/05/Untitled-design-37.png)
Cell Based Assays
Resources To Consider
![Left arrow](https://www.frontagelab.com/wp-content/themes/frontagelabs/assets/images/arrow_left.png)
![Measuring Biological Activity of Biopharmaceuticals with Cell-Based Assays](https://www.frontagelab.com/wp-content/uploads/2019/08/Cell-Based-Assay-Frontage-Lab_small-360x180.jpg)
white-paper
Measuring Biological Activity of Biopharmaceuticals with Cell-Based…
A drug’s potency, which is a critical quality attribute, is determined by examining biol…
![Development of a Neutralizing Antibody Assay to support Clinical Trials](https://www.frontagelab.com/wp-content/uploads/2017/04/BioA-Scientists-360x180.jpg)
case-study
Development of a Neutralizing Antibody Assay to support Clinical…
Frontage supported a Sponsor that required development of a Neutralizing Antibody (NAB) me…
![Antibody Drug Conjugate (ADC)](https://www.frontagelab.com/wp-content/uploads/2019/11/ADC-small-360x180.jpg)
case-study
Antibody Drug Conjugate (ADC)
In this case study, Frontage develops a multiplexed LC-MS/MS assay that generates multiple…
![Right arrow](https://www.frontagelab.com/wp-content/themes/frontagelabs/assets/images/arrow_right.png)